Journal: Gastrointestinal endoscopy

Article Title: Outcome of endoscopic mucosal resection in Barrett’s esophagus determined by systematic quantification of epithelial glands using volumetric laser endomicroscopy

doi: 10.1016/j.gie.2018.09.038

Figure Lengend Snippet: A and D, Volumetric laser endomicroscopy (VLE) scan of EMR specimens. The VLE scan is rendered to generate an en-face view of the specimen (B and E). The outline of the EMR (yellow) is selected and superimposed over a topographic map (C and F) of epithelial glands (displayed in white) generated using image visualization enhancement (IVE) software. An epithelial gland count is performed by review of each individual frame across the EMR in VLE cross-section. The total surface area (mm2) occupied by glands is quantified using the IVE en-face image. A VLE scan of an en-bloc resection specimen (R0) with a total cross-sectional gland count of 9 and a gland surface area of 0.69 mm2 with glands >0.5 mm from the specimen margin is shown in (C). A VLE scan of an incomplete resection specimen (R1) with a total cross-sectional gland count of 28 and a gland surface area of 2.0 mm2 with glands involving the specimen margin (arrow) at <0.5 mm is shown in (F).

Article Snippet: 10 Automated computer-aided epithelial gland quantification using VLE Automated image visualization enhancement (IVE) software (NinePoint Medical, Bedford, Mass) was used to visualize epithelial glands for quantification.

Techniques: Generated, Software